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doi: 10.1159/000494487 153 HoeksMYuGLangemeijerSCrouchSde SwartLFenauxPet al
Although the exact mechanism of cyclosporine nephrotoxicity remains unknown, its administration has been associated with in vivo reduction of GSH concentrations in the livers and kidneys of rats, which may be related to adverse effects of this immunosuppressive agent
The fact that there is no upregulation with the control treatment is probably due to the lack of metabolically available selenium
Key Takeaway: Standard glutathione pills are frequently dismantled by digestive enzymes before they can be absorbed
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