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However, the GLP-1 hormone has a very short half life, meaning it doesnt last very long in your system

Dehydration can amplify side effects like dizziness, headache, and constipation, creating a cycle that worsens treatment tolerance

This emphasis on long-term behavioral and psychological support is further underscored by a recent BMJ systematic review and meta-analysis showing rapid and clinically meaningful weight regain after discontinuation of weight-management medications, with regain occurring faster than after behavioral weight-management programmes [97]

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Tirzepatide: Mounjaro, Zepbound, and compounded formulations Tirzepatide is technically a dual GIP/GLP-1 receptor agonist, but it follows similar storage principles