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GLP-1 originates from the cleavage of preproglucagon, a 160-amino acid precursor whose expression, driven by the GCG gene, occurs in pancreatic -cells and intestinal cells
AION can either be non-arteritic (NAION) or arteritic (AAION) which is almost always associated with giant cell arteritis
Notably, B cells have been shown to also harbor dual roles: chemotherapy-induced ICOSL + B cells enhance T-cellmediated antitumor immunity (157), while pathological antibodies activate NF-BHIF1COX2 signaling in tumor cells to form pro-metastatic lymph node niches (158)
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The extended phase of autophagy is controlled by the LC3 coupling system [52]
