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Practical mechanism-based monitoring protocols Tracking mechanism engagement helps optimizing dosing and identifying responders

Design A proof-of-concept study - an early check that the idea works at all

Designed to penetrate the blood-brain barrier

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Folate-Independent Remethylation This is an alternative pathway that changes homocysteine back into methionine or dimethylglycine, keeping base levels of homocysteine within a healthy range ( Several nutrients are needed for this pathway to work: Trans-Sulphuration This process lowers homocysteine levels by turning it into the amino acid cysteine