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In a widely cited New England Journal of Medicine trial using once-weekly semaglutide 2.4 mg plus lifestyle intervention in adults with overweight or obesity without diabetes, participants had a substantial and sustained reduction in body weight over 68 weeks
Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D, Stambolija V, Zoricic Z, Vrcic H, Sebecic B
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Since semaglutide mimics the hormone GLP-1, which regulates appetite, it helps someone feel full for longer, reduces cravings for ultra-processed foods, and slows gastric emptying
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