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Biosynthesis of H 2 S H 2 S can be generated in mammalian physiology via dedicated endogenous enzymatic systems, gut microbiota metabolism and the breakdown of dietary polysulphide sources such as, for example, garlic and onion (reviewed e.g

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Semaglutide works by mimicking the incretin hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, and slows gastric emptying

Direct effects on liver and lipid metabolism Some research suggests that GLP-1 drugs affect how the liver makes, stores, and clears lipids