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(PubMed) Gariballa S, Ullegaddi R
Conclusions The selected biomarkers have the potential to improve the detection of RA, and may offer insights into the intervention strategies to susceptible at-risk populations of developing RA
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There is the classically activated M1 macrophage state associated with pro-inflammatory effects, anti-tumor signals, stimulation of cytotoxic T-cells, secretion of cytokines like interleukin (IL)-12, tumor necrosis factor alpha (TNF-), reactive oxygen species (ROS) and essentially activity to kill tumor cells and pathogens (60)
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