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We used multiple rigorous methods (including propensity score matching) to achieve a well-balanced analytic cohort of more than 18,000 patients to appropriately evaluate the effectiveness of semaglutide compared with tirzepatide for weight loss

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This can trigger unexpected grief in researchers whose relationship with food was deeply tied to comfort, social connection, or identity

For health system leaders, clinicians, and Medicare administrators, the announcement raises important questions about access, pricing stability, and the future role of telehealth in obesity care

(20) Liraglutide was dosed at 1.2mg/d, and low-calorie substitutions were permitted for both the control and study group as needed for weight maintenance