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That said, there's limited research specifically on women
Its half maximal inhibitory concentration (IC50) for GIPR is 42.4 nM, and its EC50 for GLP-1R is 24.4 pM in a human cell-based functional assays (74)
Considering that most current pharmacological treatments of obesity are linked to major side effects, the preclinical research into 5-amino-1MQ looks promising
That difference in intended duration is part of why combining them is not routine
TGR5, Takeda G protein receptor 5
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