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It should be noted that the protocol was not registered at the registry of systematic reviews/meta-analyses (PROSPERO)

People taking certain meds, like iron chelators, should also avoid high dose vitamin C supplements

(in women), blood pressure greater than 130/85 mmHg, fasting triglyceride level (higher than 150 mg/dL), HDL level less than 50 mg/dL, and fasting blood sugar more than 100 mg/dL [22]

The once-weekly dosing schedule removes daily pill adherence requirements, which appeals to people with busy or unpredictable routines

Its principal mechanisms include enhancing insulin secretion in response to meals, inhibiting glucagon release, and slowing gastric emptying