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Research suggests that GHS-R activation may influence not only pituitary signaling but also hypothalamic neuropeptide networks involved in appetite regulation and metabolic sensing

J Pediatr 130(6):966971 Bjrklund G (2015) Clinical use of the metal chelators calcium disodium edetate, DMPS, and DMSA

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A consequence of reduced blood flow is a lack of oxygen for the local cells