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The drug is approved in three different forms for treating T2DM by the US Food and Drug Administration (FDA)
Competitors like Ro have also embraced the compounding strategy
GLP-1R has been shown to be expressed in the renal cortex as well as the proximal tubules (Schlatter et al., 2007
For the time being, though, the market is still dominated by two names: Eli Lilly and Co
These conjugates are excreted into the duodenum via bile, where they are hydrolyzed back to GA by symbiotic bacteria, after which they can be reabsorbed (Figure 3)
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