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New blood vessels in injured tendon tissue mean better delivery of oxygen, nutrients, and resident repair cells, which is plausibly why the peptide shows up first in tendon-healing models
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The medication improves insulin sensitivity and glucose regulation, and fasting-state blood sugar is typically well-controlled
A number of studies have shown beneficial effects of GLP-1-based interventions on measures affecting cardiovascular pathologies such as blood pressure, body weight and lipid metabolism that are thought to be exerted independent of GLP-1 analogues effects on glycemic control 8,9 and the effects on markers of atherosclerosis are also reported 10,11,12
In the REDEFINE 2 trial, CagriSema achieved a 15.7% weight loss in patients with type 2 diabetes over 68 weeks
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