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[13] Both weight management treatments are time-limited and require specialist supervision

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The problem with this is that compounded formulations can be difficult to dose accurately and can sometimes lead to the overtreatment of hypothyroid (which, in turn, can lead to weight gain rather than weight loss)

When initiating semaglutide in patients already on insulin, insulin doses should be reduced gradually and carefully to avoid diabetic ketoacidosis (DKA)