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These symptoms are most common during the early stages of treatment or when doses are increased, but they often subside as the body adjusts

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semaglutide for obesity showed tirzepatide 10 mg or 15 mg produced significantly greater reductions in body weight and waist circumference over 72 weeks compared to semaglutide 1.7 mg or 2.4 mg, with both drugs having mostly mild-to-moderate gastrointestinal side effects during dose escalation