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A complete understanding of obesity-related asthma remains elusive, but it is most often characterized by the absence of hallmark features of Type-2 (T2) high asthma, such as eosinophilia or elevated exhaled nitric oxide (NO) levels
They originate deep within the cells due to oxidative stress, toxin accumulation, inflammation, and overproduction of melanin
The ApoE 2/3/4 polymorphism represents a significant genetic determinant of individual variations in lipid and lipoprotein levels [85]
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