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The rates of Achilles tendon rupture vary in the literature, with recent studies reporting 18 patients per 100,000 annually (Shamrock and Varacallo 2022)

( M ) Double immunofluorescence staining of -smooth muscle actin (left panel), GLP-1R (middle panel) and both GLP-1R and -smooth muscle actin (right panel) in Glp1r VSM+/+ and Glp1r VSM/ kidney