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Kefir peptides (KPs) intervene at multiple mechanistic levels: they reduce macrophage accumulation in plaques, suppress IL-1 and TNF- production, and diminish endothelial activation, as evidenced by decreased VCAM-1 and ICAM-1 expression both at the mRNA and protein levels

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Antioxidants 11:606

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8 Avoiding Acetaminophen/NSAID Toxicity The most effective approach to minimizing acetaminophen and NSAID toxicity would be avoiding their usage altogether and choosing alternative means for treatment of inflammation and pain (For more information, see Life Extensions Chronic Inflammation and Chronic Pain protocols)