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Gaba and the Basal Ganglia - from Molecules to Systems
The peptide N-terminus is highly conserved between GLP-1, exendin-4 and oxyntomodulin, and as such, a large number of receptor contacts are also conserved, whereas these are more divergent when compared with exendin-P5 (Supplementary Table 1)
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Wegovy slows gastric emptying through GLP-1 receptor activation, which increases satiety but also slows digestive transit time
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