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The study established a maximum tolerated dose (MTD) based on the development of dose-limiting peripheral neuropathy
Its narrow therapeutic range means even small changes can have significant effects
Although pro-oxidant profile was evident in both brain areas, differences in the magnitude of some alterations and in aconitase activity suggested that the functional consequences of oxidative stress may vary across brain regions
Half-Life and Dosing Sermorelin has a relatively short half-life of approximately 1020 minutes
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