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Stop codon in the proCollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy)

In general, unlike other types of NP (including those induced by trauma and diabetes) axonal degeneration in peripheral nerves is not present in CIPN (Ji et al., 2013)

doi: 10.1097/MOL.0b013e32832d3b9d 101

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PQQ could ameliorate the memory deficits and neurotoxicity induced by D-gal via binding with excess glutamate, which provide a link between glutamate-mediated neurotoxicity, inflammation and oxidative stress