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Setting Realistic Expectations Understanding the typical semaglutide timeline helps prevent discouragement during the early weeks when dose adjustments may cause temporary side effects and weight loss is just beginning

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There are many factors that may contribute to how GLP-1s increase a persons risk of blood clots including that people with type 2 diabetes who take Mounjaro may have an increased risk of plaque buildup in their arteries, potentially leading to blood clots

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If you need to continue increasing beyond 7.5 mg, maintain four-week intervals between increases (7.5 mg to 10 mg, then 10 mg to 12.5 mg, then 12.5 mg to 15 mg)

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The Bottom Line Eight announcements in one week sounds overwhelming, but the through-line is actually fairly clear

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Other uncommon but serious risks include pancreatitis and gallbladder disease, with gallstones occurring in a small percentage of users during rapid weight loss

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