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Functional enrichment analysis Functional enrichment analysis was performed using DAVID 2008 or Gene Set Enrichment Analysis (GSEA) v2.0.7 [16, 18]

[3] The neutral molecular structure commonly assigned to retatrutide has the molecular formula C 221 H 342 N 46 O 68 , an average molecular weight of approximately 4,731.34 Da, and an exact mass of approximately 4,728.47 Da (per KEGG DRUG entry D12528)