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November 2025: FDA approved expanded Zepbound (tirzepatide) indication for moderate-to-severe obstructive sleep apnea in adults with obesity, following SURMOUNT-OSA trial data showing 62.8% reduction in apnea-hypopnea index the first drug approval for sleep apnea treatment

Screening and data extraction After removing duplicate studies from the initial search results, two authors independently screened the titles and abstracts to exclude irrelevant articles

We have to be cautious

Lower blood volume forces the heart to contract harder to maintain blood pressure, and that increased contractility can manifest as palpitations

You can then continue with your next injection on your usual treatment day, even if there are only a few days between doses