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Lancet 375 , 8991 (2010)
For patients who need to discontinue semaglutide due to side effects, cost, or personal preference, transitioning to alternative weight management strategies is essential
Mechanism of action: Activates both GLP-1 receptors AND GIP (glucose-dependent insulinotropic polypeptide) receptors simultaneously GIP receptors in fat tissue directly regulate lipid metabolism and fat cell energy storage Dual activation creates a synergistic effect on appetite suppression and energy expenditure Produces stronger improvement in insulin sensitivity compared to GLP-1-only medications FDA-approved brand names: Zepbound approved for chronic weight management Mounjaro approved for type 2 diabetes Why does the dual mechanism matter
Storage Guidance:Store in a cool, dry and dark environment in tightly sealed original container
Its formula combines the first post-biotic active ingredient derived from Avne Thermal Spring Water, I-modulia, which reduces sensations of itching*, and fights against irritation caused by dryness, with Cer-omega, skin-like lipids that act on dryness and restore the skins barrier, and Avne Thermal Spring Water, which is naturally softening, soothing, and anti-irritating
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