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Common side effects may include mild redness, swelling, or tenderness at the injection site, brief flushing, nausea, headache, dizziness, or fatigue
An acute toxicity study in mice found that the lethal dose 50 (LD50) was more than 5 g, indicating that glutathione is nontoxic
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It should be noted that men with known conditions that would cause inflammation (such as genital tract infections, varicocele) or that used alcohol, smoked, or were currently taking antioxidants were all excluded from the study to create a more consistent base-line of existing oxidative stress (inflammation) between the groups This study also showed that the higher the measured levels of ROS, the more damage there was to sperm function
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