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Kamen DL, Tangpricha V

[7] [9] Caution is advised in individuals with renal insufficiency or those on dialysis, as impaired clearance may increase the risk of accumulation and toxicity

Small molecules can improve hepatocyte engraftment by disrupting endothelial integrity, preventing microcirculatory obstruction, and inhibiting instant blood-mediated inflammatory reaction

In these systems, core pathway inhibitors like Ferrostatin-1 and Liproxstatin-1 demonstrate robust efficacy by directly scavenging lipid radicals (Chen, 2023a