Mood disturbances, such as anxiety, depression, and irritability: These mental health symptoms can indicate a severe deficiency
These are generally dose-dependent and resolve with proper dosing adjustment
In addition, Liver cancer is more dependent on FSP1 overexpression mediated by Keap1/Nrf2 to inhibit ferroptosis, and using FSP1 inhibitor iFSP1, FSP1 effectively induces ferroptotic cell death in liver cancer and profoundly increased immune infiltrates to unleash anti-cancer immune response (Cheu et al., 2023)
12 CONCLUSION This case illustrates the benefit of multidisciplinary integration, as it shows the importance of taking into account variables of the clinical, imaging, pathological, and immunohistochemical expressions that help establish a correct diagnosis and ensure adequate therapeutic management, in addition to a continued presentation of new cases of this rare pathology.
No case reports document this happening, but the mechanistic concern is real enough to warrant disclosure