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The peptide, typically administered as a nasal spray, has shown the most promise in humans for treating neurological conditions, particularly ischemic stroke, but there is no evidence for general cognitive enhancement

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PMCID: PMC2645018

Acetyl-L-carnitine and L-arginine are two amino acids for which some studies showed potential benefits

Some studies suggest agomelatine offers benefits for initial insomnia, improvement of sleep quality and efficiency, reduced daytime sleepiness, but no changes in sleep architecture of depressed patients (97)