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Aerobic conditioning appears to neutralize the chronotropic effect that has been a persistent concern with chronic GLP-1 therapy
Rather than testing prior hypotheses about benefits and harms of these new medicines the analysts look for patterns in the data that might signal previously unsuspected effects
Phase 1 heart rate averaged +10.3 bpm over 8 days, with a higher peak around day 5
Other than how the pathways are activated, the big difference between the two is which clotting factors are involved
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