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However, other studies have attempted to address the delayed gastric emptying in patients treated with GLP-1RAs with a different and novel approach, the use of point-of-care ultrasound (POCUS)
a stable 13 C-labeled fatty acid breath test) and reliance on self-reported symptoms rather than validated symptom indices for gastrointestinal disorders are also limitations
Important gaps persist, including limited long-term safety data in vulnerable populations, incomplete monitoring of antimicrobial resistance transfer, and scarce head-to-head comparisons between strains or formulations, which hinder the development of clear, strain-specific clinical guidelines ( This review aims to (i) summarize current evidence on probiotic mechanisms and health benefits, (ii) critically evaluate therapeutic applications and associated risks, and (iii) highlight novel directions such as NGPs, engineered strains, and microbiome-targeted interventions
If rash, burning or inflammation occur, immediately remove the product from skin and discontinue all further use.