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In this study, MM/PBSA is used to calculate the binding free energy between tyrosinase (hTYR and mTYR) and inhibitors, in order to assess the strength of their interactions and screen potential binding modes with high affinity 59
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Total cost depends more on number of sessions than per-session price
This is likely to be due to their potential side effects and to limited access under insurance coverage policies and national prescribing guidelines
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