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To make the hEC surface charge more positive the glycocalyx of hECs was digested with neuraminidase enzyme (1 U/ml, 1-h pretreatment) or cultures were treated with cationic lipid 1-(4-trimethylammoniumphenyl)-6-phenyl-1,3,5-hexatriene (TMA-DPH
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This receptor is expressed on pituitary somatotrophs and, when started, boosts growth hormone release through a pathway distinct from GHRH
In the UK, the regulatory pathway for new medicines requires submission of a Marketing Authorisation Application (MAA) to the MHRA
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