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Future clinical trials should investigate the safety, timing, and dosing of ferroptosis inhibitors when combined with standard-of-care therapies
Selenium deficiency impairs the synthesis of all selenoproteins, including glutathione peroxidase
Since GLP-1 is cleaved by dipeptidyl peptidase-4 and has a half-life of less than 2 minutes, it is likely that intestinal GLP-1, released after eating, exerts its effect on the brain mainly by interacting with vagus afferent neurons located in the porta hepatis and pylorus
UA possesses a multifaceted role, such as antioxidant, pro-oxidative, pro-inflammatory, nitric oxide modulating, anti-aging, and immune effects, which are significant in both physiological and pathological contexts
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