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However, GLP-1s can come with challenges, including gastrointestinal side effects, risk of micronutrient deficiencies, muscle and bone loss, poor long-term follow through with weight regain if stopped, and high costs
At the European Association for the Study of Diabetes conference in September 2024, researchers reported that in early trials, amycretin led to a 10.4% loss of body weight in people who were overweight or obese when taken at its lowest dose for 12 weeks
Zhuo R et al
If your real goal is to even out pigmentation or brighten dull skin, there are safer, better-studied routes, which we touch on at the end
The first few weeks on tirzepatide are when GI side effects peak
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