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PMCID: PMC6880733

Despite its known effects, the physiological role of DSIP remains unclear, partly due to the lack of identification of its gene and receptor

This included circumvention of the complex downhill syndrome, as well as a sudden decrease of blood supply, decreased NO levels in the inferior caval vein tissue, an immediate heavy loss of endothelial cells from the vascular wall, a lower eNOS production ability (Rangan and Bulkley, 1993

Hypercalcemia has been reported infrequently with tamoxifen use in patients with metastatic breast cancer

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