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Tryptophan is an amino acid the body uses to make serotonin, a brain chemical that helps regulate mood

The combined GI burden is clinically meaningful and may reduce adherence to either medication

The drug also acts on the nervous system of the gut

S1 to S7 References ( 77 93 ) Download 3.00 MB Other Supplementary Material for this manuscript includes the following: Download 44.79 KB MDAR Reproducibility Checklist Download 163.52 KB Correction (29 December 2025): The group labels, which identify treated animals and controls, were inadvertently omitted from the original data deposited in the Genome Sequence Archive

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