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To report adverse reactions, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch

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For all in vitro assays the NAPstar sensor protein was quantified by Bradford assay 77 and the sensor protein was used at a final concentration of 240480 nM

642,643 These results suggest that NNMT is an appealing target for obesity and type 2 diabetes treatment

In addition, flux analysis by NMR of INS-1 cells stimulated by glucose did not support the idea that anaplerosis through GDH is associated with GSIS [76]