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Certain health conditions such as hypothyroidism, polycystic ovarian syndrome (PCOS), and type 2 diabetescan affect metabolism, hormone balance, fat distribution, appetite regulation, or energy levels, making weight loss more challenging
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doi:10.1007/s00380-004-0822-4
When a drug is in shortage, compounders may be able to prepare a compounded version of that drug if they meet certain requirements of the Federal Food, Drug, and Cosmetic (FD&C) Act, the FDA says, but the agency doesnt review these compounded versions for safety, effectiveness or quality