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PMOSs intricate pathogenesis involves disruptions in hypothalamic-pituitary-ovarian axis signaling, insulin resistance fostering hyperinsulinemia, and androgen excessall contributing to anovulation and infertility
During the first 2 to 4 weeks, patients primarily notice appetite reduction and smaller portion sizes rather than major weight changes
Conversely, the use of liraglutide in the LEADER trial led to a 22% reduction in cardiovascular deaths [53, 54, 56]
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