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Planning for long-term use, including the cost implications , is a practical necessity
At this time, there is not enough scientific evidence to consider it safe for use during pregnancy or breastfeeding, so avoiding it during these stages is generally recommended
Cell Metab 34:5974
doi: 10.1210/jc.2011-3172 34 GregoryJMSmithTJSlaughterJCMasonHRHugheyCCSmithMSet al
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