For researchers on intermediate doses like 6 mg (60 units at 10 mg/mL), results will likely fall somewhere between the 5 mg and 10 mg trial outcomes
The TRAILBLAZER-ALZ 2 (NCT04437511) trial was initially started in June 2020 as a phase 2 safety and efficacy trial, and 500 patients with early AD were recruited
The LactMed database, maintained by the National Library of Medicine, now states that tirzepatide is usually undetectable in breastmilk with subcutaneous doses of up to 5 mg and that absorption by the infant is unlikely because it is probably partially destroyed in the infant's gastrointestinal tract and poorly absorbed orally
Romano, M., Vacante, M., Cristaldi, E., Colonna, V., Gargante, M
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