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No controlled combination studies exist

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The psychiatric diagnosis of BD patients for types I/II was defined in the Manual Diagnosis and Statistics of Mental Disorders (DSM-V) and confirmed by a semi-Structured Clinical Interview, according to DSM-V (SCID-5-CV)

Several bacterial species including Streptococcus thermophilus express a bifunctional enzyme GshF , which possesses both glutamate-cysteine ligase and glutathione synthetase activities 25 (Fig