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Fatal malonyl CoA decarboxylase deficiency due to maternal uniparental isodisomy of the telomeric end of chromosome 16

This non-bound, redox-active and chelatable iron pool can be utilized in cellular metabolic processes, or, when in excess, be stored in ferritin or excreted via ferroportin

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PAS-ZHY also alleviated hepatic HFD-induced inflammation, indicated by a decreased expression of TNF-a and IL-6