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For persistent or atypical cramps, evaluate for metabolic (e.g., renal failure), endocrine (thyroid disorders), medicine-induced, and neuromuscular causes (Garrison et al., 2020)
For patients who are naturally B12 deficient, more frequent injections about once a month may be ideal
Freezing Reconstituted Peptide Freezing a liquid peptide solution forms ice crystals that can shear peptide bonds
However, the interactions have not been studied
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