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The final concentration of 25 M FOXO4-DRI was added to the cells in a DMEM containing 2% FBS or 10% FBS

Increased levels of uric acid result in inflammation and oxidative stress, which serve as potential risk factors for cellular senescence, apoptosis, and disruptions in the cell cycle

Immune Function: It supports the immune system, enhancing the body's ability to fight off infections and illnesses

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Drawing on data from eight case-control studies comprising 230 individuals with depression and 216 healthy controls, the authors examined glutathione levels across two main brain regions: the occipital cortex and the medial frontal cortex