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Novo Nordisk has completed six pchaseiia studies on Sermaglutide injection and submitted a new drug registration application for weekly injection of Sermaglutide to the US Food and Drug Administration (FDA) on December 5, 2016, as well as a marketing authorization application to the European Medicines Agency (EMA)

Constipation While some people experience diarrhea, others may have constipation

The long-acting compound contains a reactive drug-affinity-complex groupcommonly shortened to DACdesigned to bind covalently to endogenous albumin after administration

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Main measures The incidence of intestinal obstruction was compared between GLP-1RAs and each of six other classes of non-GLP-1RA anti-diabetic medications