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Long-term use of prednisone and other corticosteroids slows the creation of new bones and speeds up the breakdown of old bone
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For example, C16-carnitine (10 M) may impair mitochondrial function in rat ventricular myocytes by accelerating ROS production and increasing the probability of mitochondrial permeability transition pore (mPTP) opening, whereas low concentrations (1 and 5 M) of C16-carnitine lightly hyperpolarize the m but do not open the mPTP [293]
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It is commonly used to promote anti-aging, weight loss, and physical recovery
