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To further explore the involvement of GLP-1R signaling in the anorexigenic effect of d-allulose, we used Glp1r knockout ( Glp1r KO) mice 26

Therefore, these populations should avoid using them

"Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency"

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Dosing flexibility differs between medications, with tirzepatide offering more granular titration options through its injection format