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FSEN1 was identified as a small-molecule inhibitor of FSP1 through chemical screening 118 , and subsequent structural analyses revealed that FSEN1 occupies the substrate-binding pocket of FSP1 in a position analogous to CoQ observed in the enzyme active site, providing structural insight into inhibitor recognition 119

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Os resultados preliminares, apresentados em um congresso de gastroenterologia em 2023, sugeriram uma melhora nos escores de atividade da doena

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